Gastric emptying of two radiolabelled antacids.

Gastric emptying of two radiolabelled antacids.

The rate of gastric emptying of two antacids, magaldrate and Maalox, was investigated using scintigraphy. Successful labelling of the antacids was carried out with 99mTc. The stability of the 99mTc-labelled antacids was satisfactory and there was no difference in antacid capacity between the labelled and unlabelled antacids. The studies were carried out on 15 healthy male volunteers. After an e...

Models of gastric emptying.

Some empirical and theoretical models of the emptying behaviour of the stomach are presented. The laws of Laplace, Hooke, and Poisseuille are used to derive a new model of gastric emptying. Published data on humans are used to test the model and evaluate empirical constants. It is shown that for meals with an initial volume of larger than or equal to 300 ml, the reciprocal of the cube root of t...

Metoclopramide and gastric emptying.

Sir,—In view of increasing interest in the effect of metoclopramide on the gastric emptying rate, may I briefly describe the results of a short trial carried out in the clinical situation as an addition to the information so far available on a drug action which could be of importance to anaesthesia. Under double-blind conditions, 39 patients appearing consecutively for emergency surgery were gi...

Radionuclide imaging of gastric emptying.

Biphasic nature of gastric emptying.

The existence of a lag phase during the gastric emptying of solid foods is controversial. It has been hypothesised that among other early events, the stomach requires a period of time to process solid food to particles small enough to be handled as a liquid. At present no standardised curve fitting techniques exist for the characterisation and quantification of the lag phase or the emptying rat...